Antioxidants Network - The Studies -

The Studies

The results of a major cross-cultural epidemiologic study of Europeans found that individuals in geographic areas where plasma vitamin E concentrations were low had increased mortality from ischemic heart disease. In a comparison of plasma antioxidant levels of middle-aged men (40-59 years of age) from different European populations, there was a high inverse correlation between age-specific mortality from ischemic heart disease and lipid-standardized plasma vitamin E levels, suggesting that diets low in vitamin E were a major risk factor for heart disease.

Ischemic Heart Disease Mortality
(Death per 100,000 Males 40-59)

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In the United States, researchers at Harvard have tracked the cardiovascular health of 150,000 health professionals in a multi-year prospective epidemiological study. Men who had taken vitamin E supplements in doses of at least 200 IU per day, for at least two years, had a 37% lower relative risk of coronary heart disease compared with men who did not take supplements. Women who had an average daily intake of 200 IU for more than two years, had a 41% lower risk.

A trial of the effect of vitamin E supplementation on the risk of myocardial infarction in 2,000 patients with coronary arterial sclerosis demonstrated that vitamin E supplementation significantly decreased cardiovascular risk. The Cambridge Heart Antioxidant Study (CHAOS) found one-quarter of the number of heart attacks in the group treated with vitamin E, at either 400 or 800 IUs per day and a 77% reduction in the incidence of second heart attacks.

Information and statements regarding dietary supplements herein has not been evaluated by the Food and Drug Administration and is not intended to diagnose, treat, cure, or prevent any disease. Nor is it meant to substitute for the advice provided by your health care provider. The efficacy of antioxidant supplementation for children and during pregnancy is not established . If you have or suspect that you have a medical problem, please contact your physician.